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Research Papers

Research: Medical Complications

Research: Etiology

Research: The Maudsley Method/FBT

Research: Early Intervention

  • The relevance of body weight in the medium-term to long-term course of adolescent anorexia nervosa. Findings from a multisite studyfrom the International Journal of Eating Disorders, January 2009. "Higher BMI prior to onset of AN, higher BMI at first discharge, and lower age at first admission predicted a normal BMI (>17.5) at follow-up in a model of logistic regression."
  • The case for early intervention in anorexia nervosa: theoretical exploration of maintaining factors  from The British Journal of Psychiatry, July 2011 "Moreover, the group with an onset in adolescence but who had been ill for over 3 years had a poor response to both family and individual therapy, suggesting that unless effective treatment is given within the first 3 years of illness onset, the outcome is poor."
  • Early identification and treatment of eating disorders: prodrome to syndrome  from Early Intervention in Psychiatry
    Volume 1, Issue 1, pages 27–39, February 2007 "The onset of eating disorder psychopathology is most common in the adolescent age group with acute psychopathology perhaps less intractable in these young patients. However, the maintenance of dysfunctional eating patterns over time appears to increase the likelihood for chronicity to develop. With chronicity appearing to be a reliable predictor for poor outcome, prevention through early intervention in younger age groups would likely lead to better outcomes with the prevention of chronicity as a key goal."
  • Early intervention in eating disorders: a parent group approach. Early Interv Psychiatry. 2012 Nov;6(4):357-67. doi: 10.1111/j.1751-7893.2012.00373.x. Epub 2012 Jul 3.  "Early intervention in eating disorders (EDs) has been a neglected area. Peak onset is in adolescence, suggesting that early intervention should include parents. We synthesize findings from five key theoretical domains, and present pilot data from a phase-specific early intervention for new onset EDs in young people."

Research: Malnutrition and Re-feeding

Research: AN Outcome Predictors

The following factors seem to predict better recovery rates for patients with Anorexia Nervosa:

Research: EDs and Sports

  • Sport and Eating Disorders - Understanding and Managing the Risks, A. Currie, MD, Asian J Sports Med. June 2010
  • Prevalence of eating disorders in elite athletes is higher than in the general population, Clin J Sport Med. January 2004
  • The Female Athlete Triad: An Emerging Role for Physical Therapy, P. Papanek, J Orthop Sports Phys Ther. 2003, "Briefly, when coupled with inadequate nutrition, the high caloric expenditure of exercise training results in a sustained negative caloric balance or low energy availability, which is exquisitely sensed by the hypothalamus, initiating a complex neuroendocrine adaptive cascade. This cascade is associated with changes in the hypothalamic-pituitary-ovarian axis, such that estrogen levels are decreased, resulting in reproductive dysfunction that may include amenorrhea, oligomenorrhea, or anovulation. Low estrogen in otherwise young healthy women, like menopause, is associated with decreased bone mineral density and increased risk of fractures. The triad is not an inevitable consequence of participation in sports or physical activity at any level, however, exercise may contribute to the disruption of caloric balance."

Research: Maintaining Factors

Research: Resistance to Treatment

  • Treatment of Anorexia Nervosa against the Patient’s Will: Ethical Considerations
    by Tomas J. Silber, MD Reproduced by permission of the American Academy of Pediatrics: Silber TJ. Treatment of anorexia nervosa against the patient's will: ethical considerations. Adolesc Med State Art Rev. 2011;22(2):283-8, x. "The central issue surrounding involuntary treatment is not whether the patient lacks the capacity to consent or refuse treatment but rather the context and relationships involved in quality care. At the end it is always values that underlie and strengthen the good work. These include fundamental respect for the person, even as liberty is restricted; beneficence; and truth telling."
  • Perceived Coercion and Change in Perceived Need for Admission in Patients Hospitalized for Eating Disorders Conclusions: "Nearly half of patients with eating disorders who denied a need for treatment on admission converted to acknowledging that they needed to be admitted within 2 weeks of hospitalization."

Research: Evidence-Based Treatment 

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